| 
																
																Research Publications 
 
																
																
																		
																		
																		
																		2023
																		
																		
																		 
																			
																			
																				Kulkarni P.G., Balasubramanian N., Manjrekar R., Banerjee T., Sakharkar A. (2023) DNA methylation-mediated Mfn2 gene regulation in the brain: A role in brain trauma-induced mitochondrial dysfunction and memory deficits. doi.10.1007/s10571-023-01358-0.
																			
																			
																			
																				Choudhari J., Nimma R., Nimal S.K., Venkata S.K.T., Kundu G.C., Gacche R.N. (2023) Prosopis juliflora (Sw.) DC phytochemicals induce apoptosis and inhibit cell proliferation signaling pathways, EMT, migration, invasion, angiogenesis and stem cell markers in melanoma cell lines. Journal of Ethnopharmacology 312, 116472.
																			
																			
																				Gacche R.N. (2023) Exploring the gut microbiome for holistic human health: therapy and beyond. EC Gastroenterology and Digestive System 10, 40-41.
																			
																			
																			
	                                                                       Kumbhar N., Nimal S., Patil D., Kaiser V.F., Haupt J., Gacche R.N. (2023) Repurposing of neprilysin inhibitor ‘sacubitrilat’as an anti-cancer drug by modulating epigenetic and apoptotic regulators. Scientific Reports, 13, 9952.
																			
																			
																				Banerjee P., Kapse P., Siddique S., Kundu M., Choudhari J., Mohanty V., Malhotra D., Gosavi S.W., Gacche R.N., Kundu G.C. (2023) Therapeutic implications of cancer stem cells in prostate cancer. Cancer Biology & Medicine 20, 401-420.
                                                                   
																			
																			Pote M.S.,Gacche R.N.  (2023) ATP-binding cassette efflux transporters and MDR in cancer. Drug Discovery Today 28, 103537. 
                                                          
																			
																				Mazire P.H., Roy A. (2023) An integrative in silico and in vitro study identifies Leishmania donovani MAP kinase12 as a probable virulence factor. International Immunopharmacology, 121, 110496. 
                                                               
																			
																				Lamba S., Roy A. (2023) Demystifying the potential of inhibitors targeting DNA topoisomerases in unicellular protozoan parasites. Drug Discovery Today 28, 103574. 
                                                                
																			
																			Lodha K., Wavhal D., Bhujbal N., Mazire P., Bhujbal S., Korde A., Bagul K., Roy A., Meshram R., Shinde V. (2023) Synthesis and biological evaluation of 9-aryl-1,8-dioxo-octahydroxanthene derivatives as antileishmanial agents. Results in Chemistry 5, 100943.
                                                               
																			
																				Shelar A., Nile S.H., Singh A.V., Rothenstein D., Bill J., Xiao J., Chaskar M., Kai G., Patil, R. (2023) Recent advances in nano-enabled seed treatment strategies for sustainable agriculture: Challenges, risk assessment, and future perspectives. Nano-Micro Letters 15, 54.
 
																			
	Desai A.S., Ashok A., Edis Z., Bloukh S.H., Gaikwad M., Patil R., Pandey B., Bhagat, N., (2023) Meta-analysis of cytotoxicity studies using machine learning models on physical properties of plant extract-derived silver nanoparticles. International Journal of Molecular Sciences 24, 4220.
 
																			
	Nile S.H., Thombre D., Shelar A., Gosavi K., Sangshetti J., Zhang W., Sieniawska E., Patil R.  Kai G. (2023) Antifungal properties of biogenic selenium nanoparticles functionalized with nystatin for the inhibition of Candida albicans biofilm formation. Molecules 28, 1836. 
 
																			
	Roy N.J., Save S.N., Sharma V., Abraham B., Kuttanamkuzhi A., Sharma S., Lahiri M., Talukdar P. (2023) NAD(P)H:Quinone Acceptor Oxidoreductase 1 (NQO1) Activatable Salicylamide H+/Cl- Transporters. Chemistry. doi:10.1002/chem.202301412.
 
																			
	Roham P.H., Kamath J.J., Sharma S. (2023) Dissecting the interrelationship between COVID-19 and Diabetes Mellitus. Adv Biol (Weinh). doi:10.1002/adbi.202300107. 
 
																			
	Yadav S.S., Roham P.H., Roy S., Sharma S. (2023) Connecting islet-specific hub genes and pathways in type 2 diabetes mellitus through the bioinformatics lens. Human Gene. 36, 201177. 
 
																			
	Mondal A., Save S.N., Sarkar S., Mondal D., Mondal J., Sharma S., Talukdar P. A benzohydrazide-based artificial ion channel that modulates chloride ion concentration in cancer cells and induces apoptosis by disruption of autophagy. J. Am. Chem. Soc. 145, 9737-9745.
 Book
 
 Sharma S. 2023 Edited the book: Prognostic Epigenetics, Volume 15, 1st edition under the series Translational Epigenetics (Edited by Prof. Trygve Tollefsbol) by Elsevier Book Chapters
 
 Book Chapters
 
 1.	Kumbhar N.M., Aparna M.A., Nimal S.K., Shewale P., Barale S., Gacche R.N. (2023) New targets for old drugs: drug repurposing approach for accelerating the drug discovery engine with minimum financial inputs. In New Horizons in Natural Compound Research (pp. 315-349). Academic Press.
 
 2.	Das S.N., Kathwate G.H. (2023). Pseudomonas putida: An environment friendly bacterium. in bioremediation for sustainable environmental cleanup. (Edited by Malik A. and Garg V.K.). CRC Press/ Taylor & Francis Group)
 
																		
																		
																		
																		2022
																		
																		
																		 
																		
																				Perween N., Pekhale K., Haval G., Bose G.S., Mittal S., Ghaskadbi S., Ghaskadbi S.S. (2023) Glutaredoxin 1 from evolutionary ancient Hydra: functions in mammalian cells. Biochemistry (Moscow). 88, 667-678.
																				Kalamkar S., Bose G.S., Ghaskadbi S., Mittal S. (2022) Andrographolide and Pterostilbene inhibit adipocyte differentiation by downregulating PPARγ through different regulators. Natural Product Research. http://doi.org/10.1080/14786419.2022.2144850. 
																				Perween N., Pekhale K., Haval G., Mittal S., Ghaskadbi S., Ghaskadbi S.S. (2022). A novel thioredoxin glutathione reductase from evolutionary ancient metazoan Hydra. Biochem Biophys Res Commun. 637, 23-31.
																				Hadawale K.N., Shewale S.A., Shetye K.C., Sagarkar S., Sakharkar A.J., Bhargava S.Y. (2022) Reproductive phase related variations in the expression of neuropeptide, cocaine- and amphetamine- regulated transcript (CART) in the brain and pituitary gland of adult male Microhyla ornate. Neuroscience Letters 786, 136783.
																				Marwaha T.K., Madgulkar A., Bhalekar M., Asgaonkar K., Gacche R.N., Shewale, P. (2022) Tailoring the properties of chitosan by grafting with 2-mercaptobenzoic acid to improve mucoadhesion: in silico studies, synthesis and characterization. Progress in Biomaterials, 11, 397-408.
																				Kamble S.S., Choudhari J., Nimma R., Santosh Kumar T.V., Patil K.K., Hese S.V., Dawane B.S., Gacche R.N. (2022). Chloroxylon swietenia (Roxb.) DC induces cell death and apoptosis by down‐regulating the NF‐κB pathway in MCF‐7 breast cancer cells: In vitro and in vivo investigations. Cancer Reports 5, 10: e1600.
																				Shaikh A.L.N., Shinde A., Chavan A., Patil R., Bobade V., Mhaske P.C. (2022) Synthesis of new 3-(4-methyl-2-arylthiazol-5-yl)-5-aryl-1, 2, 4-oxadiazole derivatives as potential cytotoxic and antimicrobial agents. European Journal of Medicinal Chemistry Reports, 6, 100092.
																				Zore G., Thakre A., Abdulghani M., Bhosle K., Shelar A., Patil R., Kharat K., Karuppayil, S. (2022) Menthol inhibits Candida albicans growth by affecting the membrane integrity followed by apoptosis. Evidence-Based Complementary and Alternative Medicine, doi: 10.1155/2022/1297888 
																				Abdulghani M., Iram R., Chidrawar P., Bhosle K., Kazi R., Patil R., Kharat K., Zore, G. (2022) Proteomic profile of Candida albicans biofilm. Journal of Proteomics, 265, 104661.
																				Lamba S., Roy A. (2022) DNA topoisomerases in the unicellular protozoan parasites: unwinding the mystery. Biochemical Pharmacology 203, 115158.  
																				Mazire P.H., Saha B., Roy A. (2022) Immunotherapy for visceral leishmaniasis: A trapeze of balancing counteractive forces. International Immunopharmacology 110, 108969. 
																				Amit Roy (2022) DNA topoisomerase as drug target in unicellular protozoan parasite Leishmania donovani. Indian Journal of Physiology and Allied Sciences 28, 28-35.
																				Mazire P., Agarwal V. Roy A. (2022) Road-map of pre-clinical treatment for visceral Leishmaniasis. Drug Development Research 83, 317-327. 
																				Roham P.H., Save S.N., Sharma S. (2022) Human islet amyloid polypeptide: A therapeutic target for the management of type 2 diabetes mellitus. J Pharm Anal. 12, 556-569.
 
																				Malla J.A., Upadhyay A., Ghosh P., Mondal D., Mondal A., Sharma S., Talukdar P. Chloride Transport across Liposomes and Cells by Non-toxic 3‑(1H‑1,2,3-Triazol-1-yl)benzamides. Org Lett. 24, 4124-4128.
                                                                              
																			Singh 
																			D., 
																			Assaraf 
																			Y.G., 
																			Gacche 
																			R.N. 
																			(2022) 
																			Long 
																			non-coding 
																			RNA 
																			mediated 
																			drug 
																			resistance 
																			in breast 
																			cancer. 
																			Drug 
																			Resistance 
																			Updates 
																			63, 
																			100851.
																			Meshram 
																			R.J., 
																			Kathwate 
																			G.H.,
																			
																			Gacche 
																			R.N. 
																			(2022) 
																			Progress, 
																			evolving 
																			therapeutic/ 
																			diagnostic 
																			approaches, 
																			and 
																			challenges 
																			in the 
																			management 
																			of hepatitis 
																			C virus 
																			infections. 
																			Archives 
																			of Virology 
																			167, 
																			717-736.
																			Kumbhar 
																			N., 
																			Nimal 
																			S., 
																			Barale 
																			S., 
																			Kamble 
																			S., 
																			Bavi 
																			R., 
																			Sonawane 
																			K.,
																			
																			Gacche 
																			R. 
																			(2022) 
																			Identification 
																			of novel 
																			leads 
																			as potent 
																			inhibitors 
																			of HDAC3 
																			using 
																			ligand-based 
																			pharmacophore 
																			modeling 
																			and 
																			MD simulation. 
																			Scientific 
																			Reports 
																			12, 
																			1712.
																			Hebade 
																			M.J., 
																			Dhumal 
																			S.T., 
																			Kamble 
																			S.S., 
																			Deshmukh 
																			T.R., 
																			Khedkar 
																			V.M., 
																			Hese 
																			S.V.,
																			
																			Gacche 
																			R.N., 
																			Dawane 
																			B.S. 
																			(2022) 
																			DTP/SiO2 
																			assisted 
																			synthesis 
																			of new 
																			benzimidazole-thiazole 
																			conjugates 
																			targeting 
																			antitubercular 
																			and 
																			antioxidant 
																			activities. 
																			Polycyclic 
																			Aromatic 
																			Compounds 
																			doi.org/10.1080/10406638.2022.2056210.
																			Kolap 
																			R.M., 
																			Kakade 
																			P.S., 
																			Mankar 
																			G.D., 
																			Barmukh 
																			R.B., 
																			Gacche 
																			R.N., 
																			Zimare 
																			S.B. 
																			(2022) 
																			Bioprospection 
																			of underutilized 
																			wild 
																			Cissus 
																			woodrowii 
																			fruits 
																			for 
																			nutritional 
																			value 
																			and 
																			characterization 
																			of green-extracted 
																			antioxidant 
																			phenolic 
																			compounds. 
																			Journal 
																			of Applied 
																			Research 
																			on Medicinal 
																			and 
																			Aromatic 
																			Plants 
																			29, 
																			100371.
																			Kolap 
																			R.M., 
																			Kakade 
																			P.S.,
																			
																			Gacche 
																			R.N., 
																			Zimare 
																			S.B. 
																			(2022) 
																			Assessment 
																			of radical 
																			scavenging 
																			activity 
																			and 
																			estimation 
																			of EC50 
																			values 
																			of various 
																			extracts 
																			of leaves 
																			and 
																			roots 
																			from 
																			Lobelia 
																			nicotianifolia 
																			Roth. 
																			(Wild 
																			Tobacco) 
																			Journal 
																			of Herbs, 
																			Spices 
																			& Medicinal 
																			Plants 
																			27, 
																			343-364.
																			Rode 
																			N.R., 
																			Tantray 
																			A.A., 
																			Shelar 
																			A.V.,
																			
																			Patil 
																			R.H., 
																			Terdale 
																			S.S. 
																			(2022) 
																			Synthesis, 
																			anti-leishmanial 
																			screening, 
																			molecular 
																			docking, 
																			and 
																			ADME 
																			study 
																			of 1-amidoalkyl 
																			2-naphthol 
																			derivatives 
																			catalyzed 
																			by amino 
																			acid 
																			ionic 
																			liquid.Research 
																			on chemical 
																			intermediates. 
																			48, 
																			2391–2412.
																			Shelar 
																			A., 
																			Singh 
																			A.V., 
																			Dietrich 
																			P., 
																			Maharjan 
																			R.S., 
																			Thissen 
																			A., 
																			Didwal 
																			P.N., 
																			Shinde 
																			M., 
																			Laux 
																			P., 
																			Luch 
																			A., 
																			Mathe 
																			V., 
																			Jahnke 
																			T., 
																			Chaskar 
																			M.,
																			
																			Patil 
																			R. 
																			(2022) 
																			Emerging 
																			cold 
																			plasma 
																			treatment 
																			and 
																			machine 
																			learning 
																			prospects 
																			for 
																			seed 
																			priming: 
																			a step 
																			towards 
																			sustainable 
																			food 
																			production.RSC 
																			advances 
																			doi.org/10.1039/ 
																			D2RA00809B.
																			Maharjan 
																			R.S., 
																			Singh 
																			A.V., 
																			Hanif 
																			J., 
																			Rosenkranz 
																			D., 
																			Haidar 
																			R., 
																			Shelar 
																			A., 
																			Singh 
																			S.P., 
																			Dey 
																			A., 
																			Patil 
																			R., 
																			Zam 
																			boni 
																			P., 
																			Laux 
																			P., 
																			Luch 
																			A. (2022) 
																			Investigation 
																			of the 
																			associations 
																			between 
																			a nanomaterial’s 
																			microrheology 
																			and 
																			toxicology. 
																			ACS 
																			Omega 
																			7, 13985-13997.
																			Kasabe 
																			U.I., 
																			Kale 
																			K.B., 
																			Rode 
																			N.R., 
																			Shelar 
																			A.V.,
																			
																			Patil 
																			R.H., 
																			Mhaske 
																			P.C., 
																			Chaskar 
																			M.G. 
																			(2022) 
																			Synthesis 
																			and 
																			antifungal 
																			screening 
																			of tetramethyl 
																			hexahydro-1H-xanthene-1,8(2H)-dione 
																			derivatives 
																			as potential 
																			inhibitors 
																			of morphogenesis 
																			and 
																			biofilm 
																			formation 
																			in Candida 
																			albicans. 
																			New 
																			Journal 
																			of Chemistry.
																			Kale 
																			K.B., 
																			Shinde 
																			M.A.,
																			
																			Patil 
																			R.H., 
																			Ottoor 
																			D.P. 
																			(2022) 
																			Exploring 
																			the 
																			interaction 
																			of Valsartan 
																			and 
																			Valsartan-Zn(ll) 
																			complex 
																			with 
																			DNA 
																			by spectroscopic 
																			and 
																			in silico 
																			methods. 
																			Spectrochimica 
																			Acta 
																			Part 
																			A: Molecular 
																			and 
																			Biomolecular 
																			Spectroscopy 
																			264, 
																			120329.
																			Borkar 
																			M.R., 
																			Martis 
																			E.A.F., 
																			Nandan 
																			S.,
																			
																			Patil 
																			R.H., 
																			Shelar 
																			A., 
																			Iyer 
																			K.R., 
																			Raikuvar 
																			K., 
																			Desle 
																			D., 
																			Coutinho 
																			E.C. 
																			(2022) 
																			Identification 
																			of potential 
																			antileishmanial 
																			1,3-disubstituted-4-hydroxy-6- 
																			methylpyridin-2(1H)-ones, 
																			in vitro 
																			metabolic 
																			stability, 
																			cytotoxicity 
																			and 
																			molecular 
																			modelling 
																			studies. 
																			Chemico-Biological 
																			Interactions 
																			351, 
																			109758.
																			Joshi 
																			K.M., 
																			Shelar 
																			A., 
																			Kasabe 
																			U., 
																			Nikam 
																			L.K., 
																			Pawar 
																			R.A., 
																			Sangshetti 
																			J., 
																			Kale 
																			B.B., 
																			Singh 
																			A.V.,
																			
																			Patil 
																			R., 
																			Chaskar 
																			M.G. 
																			(2022) 
																			Biofilm 
																			inhibition 
																			in Candida 
																			albicans 
																			with 
																			biogenic 
																			hierarchical 
																			zinc- 
																			oxide 
																			nanoparticles. 
																			Materials 
																			Science 
																			and 
																			Engineering: 
																			C 134, 
																			112592.
																			
																			
																			Kathwate 
																			G.H. 
																			(2022) 
																			In silico 
																			design 
																			and 
																			characterization 
																			of multi‑epitopes 
																			vaccine 
																			for 
																			SARS‑CoV2 
																			from 
																			its 
																			spike 
																			protein. 
																			International 
																			Journal 
																			of Peptide 
																			Research 
																			and 
																			Therapeutics 
																			28, 
																			1-15.
																			Awathale 
																			S.N., 
																			Waghade 
																			A.M., 
																			Kawade 
																			H.M., 
																			Jadhav 
																			G., 
																			Choudhary 
																			A.G., 
																			Sagarkar 
																			S,
																			
																			Sakharkar 
																			A.J., 
																			Subhedar 
																			N.K., 
																			Kokare 
																			D.M. 
																			(2022) 
																			Neuroplastic 
																			changes 
																			in the 
																			superior 
																			colliculus 
																			and 
																			hippocampus 
																			in self-rewarding 
																			paradigm: 
																			importance 
																			of visual 
																			cues. 
																			Molecular 
																			Neurobiology 
																			59, 
																			890–915.
																			Kulkarni, 
																			P.G., 
																			Sakharkar, 
																			A., 
																			Banerjee, 
																			T. (2022). 
																			Understanding 
																			the 
																			role 
																			of nACE2 
																			in neurogenic 
																			hypertension 
																			among 
																			COVID-19 
																			patients. 
																			Hypertension 
																			Research 
																			45, 
																			254-269.
																			Sagarkar, 
																			S., 
																			Bhat, 
																			N., 
																			Sapre, 
																			M., 
																			Dudhabhate, 
																			B., 
																			Kokare, 
																			D.M., 
																			Subhedar, 
																			N.K., 
																			Sakharkar, 
																			A.J. 
																			(2022) 
																			TET1-induced 
																			DNA 
																			demethylation 
																			in dentate 
																			gyrus 
																			is important 
																			for 
																			reward 
																			conditioning 
																			and 
																			reinforcement. 
																			Molecular 
																			Neurobiology 
																			doi:10.1007/s12035-022-02917-0.
																			Roham 
																			P.H., 
																			Save 
																			S.N.,
																			
																			Sharma 
																			S. 
																			(2022) 
																			Human 
																			islet 
																			amyloid 
																			polypeptide: 
																			A therapeutic 
																			target 
																			for 
																			the 
																			management 
																			of type 
																			2 diabetes 
																			mellitus. 
																			Journal 
																			of Pharmaceutical 
																			Analysis 
																			https://doi.org/10.1016/j.jpha.2022.04.001.
																			Mazire 
																			P., 
																			Agarwal 
																			V., 
																			Roy 
																			A. 
																			(2022) 
																			Road-map 
																			of pre-clinical 
																			treatment 
																			for 
																			Visceral 
																			Leishmaniasis. 
																			Drug 
																			Development 
																			Research 
																			83, 
																			317-327. 
																		
																		
																		
																		2021
																		
																		
																		 
																			
																			Medha, 
																			Roy 
																			A. Microgravity: 
																			New 
																			aspect 
																			for 
																			breast 
																			cancer 
																			treatment, 
																			a review. 
																			Acta 
																			Astronautica 
																			190, 
																			62–73.
																			
																			2021.
																			Bhapkar 
																			S., 
																			Kumbhar 
																			N.,
																			
																			Gacche 
																			R., 
																			Jagtap 
																			S., 
																			Jadhav 
																			U. (2021) 
																			Photodynamic 
																			therapy 
																			(Pdt): 
																			An alternative 
																			approach 
																			for 
																			combating 
																			Covid-19. 
																			Biointerface 
																			Research 
																			in Applied 
																			Chemistry 
																			11, 
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