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Research Publications


  1. Singh D., Assaraf Y.G., Gacche R.N. (2022) Long non-coding RNA mediated drug resistance in breast cancer. Drug Resistance Updates 63, 100851.

  2. Meshram R.J., Kathwate G.H., Gacche R.N. (2022) Progress, evolving therapeutic/ diagnostic approaches, and challenges in the management of hepatitis C virus infections. Archives of Virology 167, 717-736.

  3. Kumbhar N., Nimal S., Barale S., Kamble S., Bavi R., Sonawane K., Gacche R. (2022) Identification of novel leads as potent inhibitors of HDAC3 using ligand-based pharmacophore modeling and MD simulation. Scientific Reports 12, 1712.

  4. Hebade M.J., Dhumal S.T., Kamble S.S., Deshmukh T.R., Khedkar V.M., Hese S.V., Gacche R.N., Dawane B.S. (2022) DTP/SiO2 assisted synthesis of new benzimidazole-thiazole conjugates targeting antitubercular and antioxidant activities. Polycyclic Aromatic Compounds doi.org/10.1080/10406638.2022.2056210.

  5. Kolap R.M., Kakade P.S., Mankar G.D., Barmukh R.B., Gacche R.N., Zimare S.B. (2022) Bioprospection of underutilized wild Cissus woodrowii fruits for nutritional value and characterization of green-extracted antioxidant phenolic compounds. Journal of Applied Research on Medicinal and Aromatic Plants 29, 100371.

  6. Kolap R.M., Kakade P.S., Gacche R.N., Zimare S.B. (2022) Assessment of radical scavenging activity and estimation of EC50 values of various extracts of leaves and roots from Lobelia nicotianifolia Roth. (Wild Tobacco) Journal of Herbs, Spices & Medicinal Plants 27, 343-364.

  7. Rode N.R., Tantray A.A., Shelar A.V., Patil R.H., Terdale S.S. (2022) Synthesis, anti-leishmanial screening, molecular docking, and ADME study of 1-amidoalkyl 2-naphthol derivatives catalyzed by amino acid ionic liquid.Research on chemical intermediates. 48, 2391–2412.

  8. Shelar A., Singh A.V., Dietrich P., Maharjan R.S., Thissen A., Didwal P.N., Shinde M., Laux P., Luch A., Mathe V., Jahnke T., Chaskar M., Patil R. (2022) Emerging cold plasma treatment and machine learning prospects for seed priming: a step towards sustainable food production.RSC advances doi.org/10.1039/ D2RA00809B.

  9. Maharjan R.S., Singh A.V., Hanif J., Rosenkranz D., Haidar R., Shelar A., Singh S.P., Dey A., Patil R., Zam boni P., Laux P., Luch A. (2022) Investigation of the associations between a nanomaterial’s microrheology and toxicology. ACS Omega 7, 13985-13997.

  10. Kasabe U.I., Kale K.B., Rode N.R., Shelar A.V., Patil R.H., Mhaske P.C., Chaskar M.G. (2022) Synthesis and antifungal screening of tetramethyl hexahydro-1H-xanthene-1,8(2H)-dione derivatives as potential inhibitors of morphogenesis and biofilm formation in Candida albicans. New Journal of Chemistry.

  11. Kale K.B., Shinde M.A., Patil R.H., Ottoor D.P. (2022) Exploring the interaction of Valsartan and Valsartan-Zn(ll) complex with DNA by spectroscopic and in silico methods. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 264, 120329.

  12. Borkar M.R., Martis E.A.F., Nandan S., Patil R.H., Shelar A., Iyer K.R., Raikuvar K., Desle D., Coutinho E.C. (2022) Identification of potential antileishmanial 1,3-disubstituted-4-hydroxy-6- methylpyridin-2(1H)-ones, in vitro metabolic stability, cytotoxicity and molecular modelling studies. Chemico-Biological Interactions 351, 109758.

  13. Joshi K.M., Shelar A., Kasabe U., Nikam L.K., Pawar R.A., Sangshetti J., Kale B.B., Singh A.V., Patil R., Chaskar M.G. (2022) Biofilm inhibition in Candida albicans with biogenic hierarchical zinc- oxide nanoparticles. Materials Science and Engineering: C 134, 112592.

  14. Kathwate G.H. (2022) In silico design and characterization of multi‑epitopes vaccine for SARS‑CoV2 from its spike protein. International Journal of Peptide Research and Therapeutics 28, 1-15.

  15. Awathale S.N., Waghade A.M., Kawade H.M., Jadhav G., Choudhary A.G., Sagarkar S, Sakharkar A.J., Subhedar N.K., Kokare D.M. (2022) Neuroplastic changes in the superior colliculus and hippocampus in self-rewarding paradigm: importance of visual cues. Molecular Neurobiology 59, 890–915.

  16. Kulkarni, P.G., Sakharkar, A., Banerjee, T. (2022). Understanding the role of nACE2 in neurogenic hypertension among COVID-19 patients. Hypertension Research 45, 254-269.

  17. Sagarkar, S., Bhat, N., Sapre, M., Dudhabhate, B., Kokare, D.M., Subhedar, N.K., Sakharkar, A.J. (2022) TET1-induced DNA demethylation in dentate gyrus is important for reward conditioning and reinforcement. Molecular Neurobiology doi:10.1007/s12035-022-02917-0.

  18. Malla J.A., Upadhyay A., Ghosh P., Mondal D., Mondal A., Sharma S., Talukdar P. (2022) Chloride transport across liposomes and cells by non-toxic 3-(1h-1,2,3-triazol-1-yl)benzamides. Organic Letters 24, 23, 4124–4128.

  19. Roham P.H., Save S.N., Sharma S. (2022) Human islet amyloid polypeptide: A therapeutic target for the management of type 2 diabetes mellitus. Journal of Pharmaceutical Analysis https://doi.org/10.1016/j.jpha.2022.04.001.

  20. Mazire P., Agarwal V., Roy A. (2022) Road-map of pre-clinical treatment for Visceral Leishmaniasis. Drug Development Research 83, 317-327.


  1. Medha, Roy A. Microgravity: New aspect for breast cancer treatment, a review. Acta Astronautica 190, 62–73. 2021.

  2. Bhapkar S., Kumbhar N., Gacche R., Jagtap S., Jadhav U. (2021) Photodynamic therapy (Pdt): An alternative approach for combating Covid-19. Biointerface Research in Applied Chemistry 11, 2069-5837.

  3. Gacche R.N., Gacche R.A., Chen J., Li H., Li G. (2021) Predictors of morbidity and mortality in COVID-19. European Review for Medical and Pharmacological Sciences 25, 1684-1707.

  4. Bhapkar S., Kumbhar N., Sharma P., Jagtap S., Gacche R., Barvkar V.T., Sonune D., Sonawane K.D., Jadhav U. (2021) Self-assembly of soybean peroxidase nanohybrid for activity enhancement and dye decolorization: experimental and computational studies. Journal of Biomolecular Structure and Dynamics doi:10.1080/07391102.2021.1975566.

  5. Ghosh D., Bansode S., Joshi R., Kolte B., Gacche R. (2021) Molecular elucidation of pancreatic elastase inhibition by baicalein. Journal of Biomolecular Structure and Dynamics 15,1-10.

  6. Sawant A.S., Kamble S.S., Pisal P.M., Sawant S.S., Hese S.V., Bagul K.T., Pinjari R.V., Kamble V.T., Meshram R.J., Gacche R.N. (2021) Synthesis and evaluation of N-(4-(substituted)-3-(trifluoromethyl) phenyl) isobutyramides and their N-ethyl analogous as anticancer, anti-angiogenic & antioxidant agents: In vitro and in silico analysis. Computational Biology and Chemistry 92, 107484.

  7. Adole V.A., More R.A., Jagdale B.S., Pawar T.B., Chobe S.S., Shinde R.A., Dhonnar S.L., Koli P.B., Patil A.V., Bukane A.R., Gacche R.N. (2021) Microwave prompted solvent-free synthesis of new series of heterocyclic tagged 7-arylidene indanone hybrids and their computational, antifungal, antioxidant, and cytotoxicity study.Bioorganic Chemistry 115, 105259.

  8. Tapkir S.R., Patil R.H., Galave S.A., Phadtare G.R., Khedkar V.M., Garud D.R. (2021) Synthesis, biological evaluation and molecular docking studies of quinoline-conjugated 1,2,3-triazole derivatives as antileishmanial agents. Journal of Heterocyclic Chemistry 59, 739-749.

  9. Shelar A., Singh A.V., Maharjan R.S., Laux P., Luch A., Gemmati D., Tisato V., Singh S.P., Santilli M.F., Shelar A., Chaskar M., Patil R. (2021) Sustainable agriculture through multidisciplinary seed nanopriming: prospects of opportunities and challenges. Cells 10, 2428.

  10. Routaray C.B., Choudhari V., Prakash D., Patil R., Jagtap S., Bai S., Kulkarni M.J., Kuchipudi S.V., Pai K.(2021) Quantitative proteomic analysis reveals differential modulation of crucial stage specific proteins during promastigote to amastigote differentiation in Leishmania donovani. Journal of Proteins and Proteomics 13, 17-27.

  11. Mone N.S., Bhagwat S.A., Sharma D., Chaskar M., Patil R.H., Zamboni P., Nawani N.N., Satpute S.K. (2021) naphthoquinones and their derivatives: emerging trends in combating microbial pathogens. Coatings 11, 434.

  12. Thakre A., Jadhav V., Kazi R., Shelar A., Patil R., Kharat K., Zore G., Karuppayil S.M. (2021) Oxidative stress induced by piperine leads to apoptosis in Candida albicans. Medical Mycology 59, 366-378.

  13. Perween N., Pekhale K., Haval G., Mittal S., Ghaskadbi S., Ghaskadbi S. S. (2021) Cloning and characterization of Thioredoxin 1 from the Cnidaria Hydra. The Journal of Biochemistry 171, 41–51.

  14. Kawashte G., Sonawane H., Mittal S., Borde M. (2021) Medicinal Fungi: A Natural Source of Pharmacologically Important Metabolites. In: Prasad R., Kumar V., Singh J., Upadhyaya C.P. (eds) Recent Developments in Microbial Technologies. Environmental and Microbial Biotechnology. Springer, Singapore. https://doi.org/10.1007/978-981-15-4439-2_18.

  15. Kathwate G.H., Shinde R.B, Karuppayil M. S. (2021) Non-antifungal drugs inhibit growth, morphogenesis and biofilm formation in Candida albicans. Journal of Antibiotics 74, 46–353.

  16. Balasubramanian N., Jadhav G., Sakharkar A.J. (2021) Repeated mild traumatic brain injuries perturb the mitochondrial biogenesis via DNA methylation in the hippocampus of rat. Mitochondrion doi:10.1016/j.mito.2021.09.001 2021

  17. Sagarkar S., Choudhary A.G., Balasubramanian N., Awathale S., Somalwar A., Kokare D.M., Subhedar N., Sakharkar A.J. (2021) LSD1-BDNF activity in lateral hypothalamus-medial forebrain bundle area is essential for reward seeking behavior. Progress in Neurobiology 202,102048.

  18. Balasubramanian N., Sagarkar S., Jadhav M., Shahi N., Sirmaur R., Sakharkar A.J. (2021) Role for histone deacetylation in traumatic brain injury-induced deficits in neuropeptide Y in arcuate nucleus: Possible implications in feeding behaviour. Neuroendocrinology 111, 2.

  19. Balasubramanian N., Sagarkar S., Choudhary A.G., Kokare D.M., Sakharkar A.J. (2021) Epigenetic blockade of hippocampal SOD2 via DNMT3b-mediated DNA methylation: Implications in mild traumatic brain injury-induced persistent oxidative damage. Molecular Neurobiology 58, 1162-1184.

  20. Kale S., Sarode L.P., Kharat A., Ambulkar S., Prakash A., Sakharkar A.J., Ugale R.R. (2021) Protocatechuic acid prevents early hour ischemic reperfusion brain damage by restoring imbalance of neuronal cell death and survival proteins. Journal of Stroke and Cerebrovascular Diseases. 30,105507.

  21. Dubey R., Kulkarni S.H., Dantu S.C., Panigrahi R., Sardesai D.M., Malik N., Acharya J.D., Chugh J., Sharma S., Kumar A. (2021) Myricetin protects pancreatic β-cells from human islet amyloid polypeptide (hIAPP) induced cytotoxicity and restores islet function. Biological Chemistry 402, 179-194.

  22. Mondal A, Malla J.A., Paithankar H., Sharma S., Chugh J., Talukdar P. (2021) A pyridyl-linked benzimidazolyl tautomer facilitates prodigious H+/Cl– symport through a cooperative protonation and chloride ion recognition. Organic Letters 23, 6131–6136.

  23. Roy A., Behera S., Mazire P.H., Kumari B., Mandal A., Purkait B., Ghosh P., Das P., Das P. (2021) The HIV-1 protease inhibitor Amprenavir targets Leishmania donovani topoisomerase I and induces oxidative stress-mediated programmed cell death. Parasitology International 82, 102287.


  1. More RA, Sanap GB, Karale MA, Sarnikar YP, Gacche RN (2020). “Antioxidant and Cytotoxicity Profile of the Selected Alcoholic Beverages Widely Consumed in the Maharashtra State of India”. Indian Journal of Public Health Research & Development. 11(6):607-12.

  2. Meshram RJ, Shirsath A, Aouti S, Bagul K, Gacche RN (2020). “Molecular modeling and simulation study of homoserine kinase as an effective leishmanial drug target”. J Mol Model.26(8):218.

  3. Meshram RJ, Bagul KT, Aouti SU, Shirsath AM, Duggal H, Gacche RN (2020). “Modeling and simulation study to identify threonine synthase as possible drug target in Leishmania major”. Mol Divers 2020 Jul 31. doi: 10.1007/s11030-020-10129-8.

  4. Patil, A., Duggal, H., Bagul, K. T., Kamble, S., Lokhande, P., Gacche RN., & Meshram, R. (2020). “Synthesis of new 3-arylaminophthalides and 3-indolyl-phthalides using ammonium chloride, evaluation of their anti-mycobacterial potential and docking study.” Combinatorial chemistry & high throughput screening, 10.2174/1386207323666200422082754. Advance online publication. https://doi.org/10.2174/1386207323666200422082754

  5. Ajay S Sawant, Sonali S Kamble, Parshuram M Pisal, Rohan J Meshram, Sanjay S Sawant, Vilas A Kamble, Vinod T Kamble, Gacche, RN.,. (2020). “Synthesis and evaluation of a novel series of 6-bromo-1-cyclopentyl-1H-indazole-4-carboxylic acid- substituted amide derivatives as anti-cancer, anti-angiogenic and antioxidant agents”. Medicinal Chemistry Research 29 (1), 17-32

  6. Gholap, H., Gholap, A., & Patil, R. (2020). “ZnO/CdS Nanocomposite: An Anti-Microbial and Anti-Biofilm Agent”. Advances in Microbiology, Vol.10 (04), 14.

  7. Khater, M., Khater, S. S., Gholap, H., Patil, R., & Kulkarni, G. (2020). “Comparative studies on measurement of membrane potential of bacterial cells treated with ZnO nanoparticles by Spectrofluorometry, fluorescence microscopy and flowcytometry”. Journal of Microbiological Methods, 173, 105920.

  8. Khater, M. S., Kulkarni, G. R., Khater, S. S., Gholap, H., & Patil, R. (2020). “Study to elucidate effect of titanium dioxide nanoparticles on bacterial membrane potential and membrane permeability”. Materials Research Express, 7(3), 035005.

  9. Sarkar, J., Kamble, S. C., Patil, R., Kumar, A., & Gosavi, S. W. (2020). “Gelatin interpenetration in poly N-isopropylacrylamide network reduces the compressive modulus of the scaffold: A property employed to mimic hepatic matrix stiffness”. Biotechnol Bioeng, 117(2), 567-579.

  10. Puri S, Kaur G, Piplani H, Sanyal SN, Vaish V., (2020). “Imatinib modulates pro-inflammatory microenvironment with angiostatic effects in experimental lung carcinogenesis”. Inflammopharmacology 28(1):231-252.

  11. Dhiman DK, Sanyal SN, Vaish V. (2020) “Imatinib exhibit synergistic pleiotropy in the prevention of colorectal cancer by suppressing proinflammatory, cell survival and angiogenic signalling”. Cell Signal. 76:109803.  doi: 10.1016/j.cellsig.2020.109803.

  12. Smriti Mittal, Shrirang Inamdar, Jhankar Acharya, Komal Pekhale, Saurabh Kalamkar, Ramanamurthy Boppana, Saroj Ghaskadbi (2020). “miR-3666 inhibits development of hepatic steatosis by negatively regulating PPARγ”. BBA Molecular and Cell Biology of Lipids, 1865(10):158777.

  13. Kathwate GH. (2020) “In silico design and characterization of multiepitopes vaccine for SARS-CoV2 from its Spike proteins”. bioRxiv, doi: https://doi.org/1101/2020.06.03.131755.

  14. Walunj RM, Natu AD, Chikate RC, Paradkar MV, Narwade SC, Kathwate GH, Deobagkar DD. (2020) “A non-lithiation route towards facile synthesis of bioactive 4, 9-dimethoxynaphthalide”. Synthetic Communications.50:20, 3125-3132

  15. Balasubramanian, N., Srivastava, A., Pawar, N., Sagarkar, S., & Sakharkar, A. J. (2020). “Repeated mild traumatic brain injury induces persistent variations in mitochondrial DNA copy number in mesocorticolimbic neurocircuitry of the rat.” Neuroscience research, 155, 34–42.

  16. Matharu D, Dhotre D, Balasubramanian N, Pawar N, Sagarkar S, Sakharkar AJ. (2020). “Repeated mild traumatic brain injury affects microbial diversity in the rat jejunum”. Journal of Biosciences 44:120.

  17. Somalwar AR, Choudhary AG, Nagalaksmi B, Sakharkar AJ, Subhedar NK, Kokare DM. (2020) “Cocaine- and amphetamine-regulated transcript peptide promotes reward seeking behavior in socially isolated rats”. Brain Research 1728:146595.

  18. Upadhya MA, Upadhya HM, Borkar CD, Choudhary AG, Singh U, Chavan P, Sakharkar A, Singru P, Subhedar NK, Kokare D. (2020). “Nicotine-induced brain stimulation reward is modulated by melanocortin-4 receptors in ovariectomized rats”. Neuroscience 431:205-221.

  19. Vijayalaxmi, Sakharkar AJ, Ganesh CB. (2020). “Leucine-enkephalin-immunoreactive neurons in the brain of the cichlid fish Oreochromis mossambicus”. Neuropeptides 81-

  20. Datir SS, Yousf S, Sharma S, Kochle M, Ravikumar A, Chugh J. (2020) “Cold storage reveals distinct metabolic perturbations in the processing and non-processing cultivars of potato (Solanum tuberosum L.)”. Sci Rep. 10(1):6268.

  21. Malla JA, Umesh RM, Yousf S, Mane S, Sharma S, Lahiri M, Talukdar P. (2020). “A Glutathione Activatable Ion Channel Induces Apoptosis in Cancer Cells by Depleting Intracellular Glutathione Levels”. Angewandte Chemie International Edition. 59(20):7944-52.


  1. Rafik U. Shaikh Rohan J.Meshram, Gacche, RN., (2019). “An investigation on in vitro anti-inflammatory and antiproliferative potential of isolated Labdane diterpenoids from Andrographis paniculata (Burm. f.) Wall. ex Nees: an important medicinal plant prescribed in Ayurveda”. European Journal of Integrative Medicine 32, 100983.

  2. Baban S Kolte, Sanjay R Londhe; Kamini T Bagul; Shristi P Pawnikar; Mayuri B Goundge; Rohan Meshram, Gacche, RN., (2019). “FlavoDb: A web based chemical repository of Flavonoid compounds”. 3Biotech 9, 431,

  3. Sonali S. Kamble, Shrikant V. Hese, Bhaskar S. Dawane, Gacche, RN. (2019). “Anti-breast cancer and antiangiogenic potential of substituted thiazolo [2,3-b] quinazoline derivatives: synthesis, in vitro and in vivo analysis”. Chemistry & Biology Interface 9(3), 137-147.

  4. Sneha B. Bansode, Gacche, RN. (2019). “Glycation-induced modification of tissue-specific ECM proteins: A pathophysiological mechanism in degenerative diseases”. BBA - General Subjects 1863, 129411.

  5. Patil KK and Gacche RN. (2019). “The Fate of Aldose Reductase Inhibition and Sorbitol Dehydrogenase Activation”. Austin J Endocrinol Diabetes, 6(1): 1064.

  6. Rohan J Meshram, Kamini T Bagul, Shristi P Pawnikar, Sagar H Barage, Baban S Kolte & Gacche, RN., (2019) “Known compounds and new lessons: structural and electronic basis of flavonoid based bioactivities”. Journal of Biomolecular Structure and Dynamics 38(4):1168-1184.

  7. Ajay N. Ambhore, Sonali S. Kamble, Shuddhodan N. Kadam, Rahul D. Kamble, Madhav J. Hebade, Shrikant V. Hese, Milind V. Gaikwad, Rohan J. Meshram, Bhaskar S. Dawane, Gacche, RN. (2019). “Design, synthesis and in silico study of pyridine based 1,3,4-oxadiazole embedded hydrazinecarbothioamide derivatives as potent anti-tubercular agent”. Computational Biology and Chemistry 80 (2019) 54–65.

  8. Kapil K Patil, Rohan J Meshram, Sagar H Barage, Gacche, RN., (2019). “Dietary flavonoids inhibit the glycation of lens proteins: implications in the management of diabetic cataract”. 3Biotech,9(2):47

  9. Sonali S. Kamble and Gacche R.N. (2019). “Evaluation of Anti-breast cancer, Antiangiogenic and Antioxidant Properties of Selected Medicinal Plants”. European Journal of Integrative Medicine 25, 13-19.

  10. Vikram Singh, A., Hasan Dad Ansari, M., Wang, S., Laux, P., Luch, A., Kumar, A., Patil, R.Nussberger, S. (2019). “The Adoption of Three-Dimensional Additive Manufacturing from Biomedical Material Design to 3D Organ Printing”. Applied Sciences, 9(4).

  11. Shaikh, A. F., Tamboli, M. S., Patil, R., Bhan, A., Ambekar, J. D., & Kale, B. B. (2019). “Bioinspired Carbon Quantum Dots: An Antibiofilm Agents. Journal of Nanoscience and Nanotechnology”, 19(4), 2339-2345.

  12. Shelar, A., Sangshetti, J., Chakraborti, S., Singh, A. V., Patil, R., & Gosavi, S. (2019). “Helminthicidal and Larvicidal Potentials of Biogenic Silver Nanoparticles Synthesized from Medicinal Plant Momordica charantia”. Medicinal Chemistry, 15(7), 781-789.

  13. Samb-Joshi, K. M., Sethi, Y. A., Ambalkar, A. A., Sonawane, H. B., Rasale, S. P., Panmand, R. P., Patil, R., Chaskar, M. G. (2019). “Lignin-Mediated Biosynthesis of ZnO and TiO2 Nanocomposites for Enhanced Antimicrobial Activity”. Journal of Composite Science, 3(3), 90.

  14. Pawar, S. V., Upadhyay, P. K., Burade, S., Kumbhar, N., Patil, R., & Dhavale, D. D. (2019). Synthesis and anti-leishmanial activity of TRIS-glycine-β-alanine dipeptidic triazole dendron coated with nonameric mannoside glycocluster. Carbohydrate Research, 485, 107815.

  15. Khan, F. A. K., Kaduskar, R. N., Patil, R., Patil, R., Ansari, S. A., Alkahtani, H. M., Sangshetti, J. N. (2019). “Synthesis, biological evaluations and computational studies of N-(3-(-2-(7-Chloroquinolin-2-yl)vinyl) benzylidene)anilines as fungal biofilm inhibitors”. Bioorganic & Medicinal Chemistry Letters, 29(4), 623-630.

  16. Halbandge, S. D., Jadhav, A. K., Jangid, P. M., Shelar, A. V., Patil, R. H., & Karuppayil, S. M. (2019). “Molecular targets of biofabricated silver nanoparticles in Candida albicans”. The Journal of Antibiotics, 72(8), 640-644.

  17. Ingle, S., Kazi, R., Patil, R., & Zore, G. (2019). “Proteome analysis of Candida albicans cells undergoing chlamydosporulation”. Journal of Proteins and Proteomics, 10(4), 269-290.

  18. Ansari, S. A., Deshmukh, S. U., Patil, R., Damale, M. G., Patil, R. H., Alkahtani, H. M., .Sangshetti, J. N. (2019). “Identification of Promising Biofilm Inhibitory and Cytotoxic Quinazolin-4-one Derivatives: Synthesis, Evaluation, Molecular Docking and ADMET Studies”. ChemistrySelect, 4(12), 3559-3566.

  19. Chadar, D., Banerjee, P., Saha, S. K., Bhand, S., Patil, R., & Salunke-Gawali, S. (2019). “n-alkylamino analogs of Vitamin K3: Electrochemical, DFT and anticancer activity of their oxidized and one electron reduced form”. Journal of Molecular Structure, 1179, 443-452.

  20. Nitin Narwade, Sonal Patel, Aftab Alam, Samit Chattopadhyay, Smriti Mittal and Abhijeet Kulkarni* (2019). “Mapping of scaffold/matrix attachment regions in human genome: A data mining exercise”. Nucleic Acids Research. 47, 7247–7261.

  21. Swati Khole, Smriti Mittal, Nidhi Jagadish, Debjani Ghosh, Sharmilli Chettiar, Vivek Singh, Aarti Desai, Vilas Sinkar, Vijay Gadgil, Saroj Ghaskadbi (2019). “Andrographolide enhances redox status of liver cells through differential microRNA expression”. Free Radical in Biology and Medicine. 130, 397-407.

  22. Sajjad A Malik, Swati Khole, Smriti Mittal, Urmode, R Kusurkar, Saroj Ghaskadbi (2019). “Differential response of antioxidant defense in HepG2 cells on exposure of Livotrit®, in a concentration dependent manner”. J. Trad. Compl. Med. 9, 38-44.

  23. Borkar CD, Sagarkar S, Sakharkar AJ, Subhedar NK, Kokare DM. (2019) “Neuropeptide CART prevents memory loss attributed to withdrawal of nicotine following chronic treatment in mice”. Addiction Biology 24(1):51-64.

  24. Singh O, Pradhan DR, Nagalakashmi B, Kumar S, Mitra S, Sagarkar S, Sakharkar AJ, Lechan RM, Singru PS. (2019) “Thyrotropin-releasing hormone (TRH) in the brain and pituitary of the teleost, Clarias batrachus and its role in regulation of hypophysiotropic dopamine neurons”. J Comp Neurol. 527(6):1070-1101.

  25. Berkel TDM, Zhang H, Teppen T, Sakharkar A, Pandey SC. (2019). “Essential role of histone methyltransferase G9a in rapid tolerance to the anxiolytic effects of alcohol”. International Journal of Neuropsychopharmacology 22: 292-302.

  26. Sagarkar S, Nagalakshmi B, Mishra S, Choudhary A, Kokare DM, Sakharkar AJ. (2019) “Repeated mild traumatic brain injury causes persistent changes in histone deacetylase function in hippocampus: Implications in learning and memory deficits in rats”. Brain Research 1711:183-192.

  27. Hadawale KN, Sawant NS, Sagarkar S, Sakharkar AJ, Bhargava SY. (2019). “Sex-specific distribution of neuropeptide Y (NPY) in the brain of the frog, Microhyla ornate”. Neuropeptides 74: 1-10.

  28. Sakharkar AJ, Kyzar EJ, Gavin DP, Zhang H, Chen Y, Krishnan HR, Grayson DR, Pandey SC. (2019). “Altered amygdala DNA methylation mechanisms after adolescent alcohol exposure contribute to adult anxiety and alcohol drinking”. Neuropharmacology 157:107679.

  29. Yousf S, Sardesai DM, Mathew AB, Khandelwal R, Acharya JD, Sharma S, Chugh J. (2019). “Metabolic signatures suggest o-phosphocholine to UDP-N-acetylglucosamine ratio as a potential biomarker for high-glucose and/or palmitate exposure in pancreatic β-cells”. Metabolomics. 29;15(4):55.

  30. Dubey R, Patil K, Dantu SC, Sardesai DM, Bhatia P, Malik N, Acharya JD, Sarkar S, Ghosh S, Chakrabarti R, Sharma S, Kumar A (2019). “Azadirachtin inhibits amyloid formation, disaggregates pre-formed fibrils and protects pancreatic β-cells from human islet amyloid polypeptide/amylin induced cytotoxicity”. Biochem J. 476:889–907.

  31. Books and Book Chapters

    1. Sharma S and Aazmi O. (2019) “Basics of Epigenetics: It is more than simple changes in gene sequence that govern expression of genes”. Elsevier Prognostic Epigenetics. 2019: Vol. 15. Pg 1-21.

    2. Kalyani A, Jha RM, Sharma S. (2019) “Use of circulating nucleic acids, metabolites, and proteins as Clinical Biomarkers for earlier prognosis and diagnosis of disease”. Elsevier Prognostic Epigenetics. 2019: Vol. 15. Pg 85-116.

    3. Sharma S. (2019) “Conclusions and perspectives: Future challenges and prospects for prognostic epigenetics”. Elsevier Prognostic Epigenetics. 2019: Vol. 15. Pg 397-410.


  1. Utage B.G., Patole M.S., Nagvenkar P., Kamble S.S., Gacche R.N. (2018). “Prosopis juliflora (Sw.), DC induces apoptosis and cell cycle arrest in triple negative breast cancer cells: in vitro and in vivo investigations”. Oncotarget 9 (54), 30304-30323.

  2. Gacche R.N., Yehuda G. Assaraf, (2018). “Redundant Angiogenic Signaling and Tumor Drug Resistance”. Drug Resistance Updates 36, 47-76.

  3. Kolte BS, Londhe SR, Solanki BR, Gacche RN, Meshram RJ. (2018). “FilTer BaSe: A web accessible chemical database for small compound libraries”. J Mol Graph Model. 80, 95-103.

  4. Gacche RN, Kamble S. (2018). “Breast Cancer: Forecasting an Evolving Ecosystem”. J Cancer Res Forecast. 11(1): 1005.

  5. Rohan J Meshram, Mayuri B Goundge, Baban S Kolte, Gacche, RN.,. (2018). “An in silico approach in identification of drug targets in Leishmania: a subtractive genomic and metabolic simulation analysis”. J. Parasitology International 69, 59-70.

  6. Meshram RJ, Dangre AM, Gacche RN. (2018). “In silico Modeling and Drug Interaction Analysis of Molecular Structure of Ecto-Domain of E1 Glycoprotein of HCV”. Int J Proteom Bioinform 3(1): 001-006.

  7. Ahmed, R., Kodgire, S., Santhakumari, B., Patil, R., Kulkarni, M., & Zore, G. (2018). “Serum responsive proteome reveals correlation between oxidative phosphorylation and morphogenesis in Candida albicans ATCC10231”. Journal of Proteomics, 185, 25-38.

  8. Ali, A., Jadhav, A., Jangid, P., Patil, R., Shelar, A., & Karuppayil, S. M. (2018). “The human muscarinic acetylcholine receptor antagonist, Dicyclomine targets signal transduction genes and inhibits the virulence factors in the human pathogen, Candida albicans”. The Journal of Antibiotics, 71(4), 456-466.

  9. Patil, R., Kalam Khan, F. A., Jadhav, K., Damale, M., Akber Ansari, S., Alkahtani, H. M., Sangshetti, J. N. (2018). “Fungal biofilm inhibition by piperazine-sulphonamide linked Schiff bases: Design, synthesis, and biological evaluation”. Archiv der Pharmazie, 351(3-4), 1700354.

  10. Patil, S. R., Bollikonda, S., Patil, R., Sangshetti, J. N., Bobade, A. S., Asrondkar, A., Shinde, D. B. (2018). “Microwave-assisted synthesis of novel 5-substituted benzylidene amino-2-butyl benzofuran-3-yl-4-methoxyphenyl methanones as antileishmanial and antioxidant agents”. Bioorganic & Medicinal Chemistry Letters, 28(3), 482-487.

  11. Larsen KM, Minaya MK, Vaish V, Peña MMO (2018). “The Role of IL-33/ST2 Pathway in Tumorigenesis”. Int J Mol Sci.19(9):2676.

  12. Kathwate SH, Kamble SV, Karuppayil SM, Zubaidha PK, Khan IA, Asiri AM.(2018) “Synthesis antioxidant and antifungal activity of Conjugated chalcones and their derivatives”. Journal of Research in Pharmacy and Chemistry.; 8(1), 123-130

  13. Nagalakshmi B, Sagarkar S, Sakharkar A. (2018). “Epigenetics of traumatic brain injuries”. Progress in Molecular Biology and Translational Science, 157:263-288.

  14. Choudhary AG, Somalwar AR, Sagarkar S, Rale A, Sakharkar AJ, Subhedar NK, Kokare M. (2018) “CART neurons in the lateral hypothalamus communicate with the nucleus accumbens shell via glutamatergic neurons in paraventricular thalamic nucleus and modulate reward behavior”. Brain Structure and Function 223:1313-1328.

  15. Borkar C, Bharne A, Nagalakshmi B, Sakharkar AJ, Subhedar N, Kokare D. (2018) “Cocaine- and amphetamine-regulated transcript peptide (CART) alleviates MK-801 induced schizophrenic dementia-like symptoms”. Neuroscience 375:94-107.

  16. Somalwar AR, Choudhary AG, Sharma PR, B N, Sagarkar S, Sakharkar AJ, Subhedar NK, Kokare DM. (2018) “Cocaine- and amphetamine-regulated transcript peptide (CART) induced reward behavior is mediated via Gi/o dependent phosphorylation of PKA/ERK/CREB pathway”. Behav Brain Res. 348:9-21.

  17. Eigil Kjeldsen, Christine J.F. Nielsen, Amit Roy, Cinzia Tesauro, Ann-Katrine Jakobsen, Magnus Stougaard and Birgitta R. Knudsen (2018). “Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5”. Cancer Genomics and Proteomics, 15: 91-114.

  18. Paithankar H, Jadhav PV, Naglekar AS, Sharma S, Chugh J (2018). “1H, 13C and 15N resonance assignment of domain 1 of trans-activation response element (TAR) RNA binding protein isoform 1 (TRBP2) and its comparison with that of isoform 2 (TRBP1)”. Biomol NMR Assign.12(1):189-194.


  1. Kapil K. Patil, Gacche, RN., (2017). “Inhibition of glycation and aldose reductase activity using dietary flavonoids: A lens organ culture studies”. International Journal of Biological Macromolecules 98, 730-738

  2. Meshram, R. J., Baladhye, V. B., Gacche, RN., Karale, B. K., & Gaikar, R. B. (2017). “Pharmacophore Mapping Approach for Drug Target Identification: A Chemical Synthesis and in Silico Study on Novel Thiadiazole Compounds.” Journal of clinical and diagnostic research, 11(5), KF01–KF08.

  3. John M, Gacche, RN., (2017). “Nano-formulations for Ophthalmic Treatments”. Arch Pharm Pharma Sci.10, 028-035.

  4. Ajay N Ambhore, Rahul D Kamble, Pratima P Mogle, Shrikant V Hese,Shuddhodan N Kadam, Madhav J Hebade, Sonali S Kamble, Gacche, RN., ,Bhaskar S Dawane (2017). “An Efficient One-pot Synthesis of some New Pyrazolyl Appended 1,3,4-Oxadiazole Derivatives as Antibacterial and Antioxidant agents”. Der Pharma Chemica, 9(9):48-56.

  5. Ingle, S., Kodgire, S., Shiradhone, A., Patil, R., & Zore, G. (2017). “Chlamydospore Specific Proteins of Candida albicans”. Data, 2(3).

  6. Jadhav, A., Bansode, B., Phule, D., Shelar, A., Patil, R., Gade, W., Karuppayil, S. M. (2017). “The antibacterial agent, moxifloxacin inhibits virulence factors of Candida albicans through multitargeting”. World Journal of Microbiology and Biotechnology, 33(5), 96.

  7. Jadhav, A., Mortale, S., Halbandge, S., Jangid, P., Patil, R., Gade, W., Karuppayil, S. M. (2017). “The Dietary Food Components Capric Acid and Caprylic Acid Inhibit Virulence Factors in Candida albicans Through Multitargeting”. Journal of Medicinal Food, 20(11), 1083-1090.

  8. Jadhav, A. K., Jangid, P., Patil, R., Gade, W., Kharat, K., & Karuppayil, S. M. (2017). “Phenazine Methosulphate Modulating the Expression of Genes Involved in Yeast to Hyphal Form Signal Transduction in Candida albicans”. Advances in Microbiology, 7(11), 707-718.

  9. Khan, F. A. K., Zaheer, Z., Sangshetti, J. N., Patil, R., & Farooqui, M. (2017). “Antileishmanial evaluation of clubbed bis(indolyl)-pyridine derivatives: One-pot synthesis, in vitro biological evaluations and in silico ADME prediction”. Bioorganic & Medicinal Chemistry Letters, 27(3), 567-573.

  10. Patil SR, Asrondkar A, Patil V, Sangshetti JN, Khan FA, Damale MG, Patil R., Bobade AS, Shinde DB. (2017). “Antileishmanial potential of fused 5-(pyrazin-2-yl)-4H-1, 2, 4-triazole-3-thiols: synthesis, biological evaluations and computational studies”. Bioorganic & Medicinal Chemistry Letters. 15;27(16):3845-50.

  11. Thakre, A., Zore, G., Kodgire, S., Kazi, R., Mulange, S., Patil, R., Karuppayil, S. M. (2017). “Limonene inhibits Candida albicans growth by inducing apoptosis”. Medical Mycology, 56(5), 565-578.

  12. Vaish V, Kim J, Shim M (2017). “Jagged-2 (JAG2) enhances tumorigenicity and chemoresistance of colorectal cancer cells”. Oncotarget.7;8(32):53262-53275.

  13. Hoda Aayadi, Smriti Mittal, Anjali Deshpande, Makarand Gore, Saroj Ghaskadbi (2017). “Cytoprotective effect exerted by geraniin in HepG2 cells is through microRNA mediated regulation of BACH-1 and HO-1”. BMB Reports, 50(11):560-565.

  14. Hoda Aayadi, Smriti Mittal, Anjali Deshpande, Makarand Gore, Saroj S Ghaskadbi (2017). “Protective effect of geraniin against carbon tetrachloride induced acute hepatotoxicity in Swiss albino mice”. Biochem Biophys Res Commun. 487, 62-67.

  15. Dofe VS, Sarkate AP, Lokwani DK, Kathwate SH, Gill CH (2017). “Synthesis, antimicrobial evaluation, and molecular docking studies of novel chromone based 1, 2, 3-triazoles”. Research on Chemical Intermediates. 1;43(1):15-28.

  16. Dofe VS, Sarkate AP, Kathwate SH, Gill CH (2017). “Synthesis, antimicrobial activity and anti-biofilm activity of novel tetrazole derivatives”. Heterocyclic Communications. 23(4):325-30.

  17. Dofe VS, Sarkate AP, Lokwani DK, Shinde DB, Kathwate SH, Gill CH (2017). “Novel O‐Alkylated Chromones as Antimicrobial Agents: Ultrasound Mediated Synthesis, Molecular Docking and ADME Prediction”. Journal of Heterocyclic Chemistry. 54(5):2678-85.

  18. Sagarkar S, Mahajan S, Choudhary A, Borkar CD, Kokare DM, Sakharkar AJ. (2017) “Traumatic stress-induced persistent changes in DNA methylation regulate neuropeptide Y expression in rat jejunum”. Neurogastroenterology and Motility 29(9).

  19. Kyzar EJ, Zhang H, Sakharkar AJ, Pandey SC (2017). “Adolescent alcohol exposure alters lysine demethylase 1 (LSD1) expression and histone methylation in the amygdala during adulthood”. Addiction Biology 22(5):1191-1204.

  20. Kokare DM, Kyzar EJ, Zhang H, Sakharkar AJ, Pandey SC. (2017) “Adolescent alcohol exposure-induced changes in alpha-melanocyte stimulating hormone and neuropeptide Y pathways via histone acetylation in the brain during adulthood”. Int J Neuropsychopharmacol. 20(9):758-768.

  21. Sagarkar S, Bhamburkar T, Chaudhary A, Shelkar G, Kokare M, Sakharkar AJ. (2017) “Minimal traumatic brain injury causes persistent changes in DNA methylation at BDNF gene promoters in the amygdala of rat: A possible role in anxiety-like behaviors”. Neurobiology of Disease 106:101-109.

  22. Manoj Kumar Singh, Siddhartha Kumar Bhaumik, Subir Karmakar, Joydeep Paul, Sudeshna Sawoo, Hemanta K. Majumder and Amit Roy (2017) “Copper Salisylaldoxime (CuSAL) Imparts Protective efficacy against visceral leishmaniasis by Targeting Leishmania donovani Topoisomerase IB”. Experimental Parasitology, 175:8-20.

  23. Dubey R, Minj P, Malik N, Sardesai DM, Kulkarni SH, Acharya JD, Bhavesh NS, Sharma S, Kumar A (2017). “Recombinant human islet amyloid polypeptide forms shorter fibrils and mediates β-cell apoptosis via generation of oxidative stress”. Biochemical Journal. 1;474(23):3915-34.

  24. Books and Book Chapters

    1. Yousf S, Hussain N, Sharma S, Chugh J. (2017) “Identification & Characterization of Secondary Metabolites in the Biological Soup by NMR Spectroscopy”. Bentham Science Applications of NMR Spectroscopy. 2017; Vol 6. Pg 47-96.

    2. Sharma S, Mathew AB, Chugh J. (2017) “miRNAs: nanomachines that micromanage the pathophysiology of Diabetes mellitus”. Elsevier Advances in Clinical Chemistry. 82:199-264.


  1. Datir S and Joshi, S. (2016). Studies on sucrose metabolizing enzymes in different sugar cane cultivars. Indian Journal of Plant Physiology, An Int J of Plant Physiology, 21(1):76-82.

  2. Datir, S. & Joshi, S. (2016). The contribution of sucrose metabolism enzymes to sucrose accumulation in sugarcane (Saccharumofficinarum L.) genotypes. Ind J Plant Physiol. 21: 76.

  3. Dubey, R., Minj, P., Malik, N., Sardesai, D.M., Kulkarni, S.H., Acharya, J.D., Bhavesh, N.S., Sharma, S., Kumar, A. (2017). Recombinant human islet amyloid polypeptide forms shorter fibrils and mediates β-cell apoptosis via generation of oxidative stress

  4. Ganga Reddy, V., Srinivasa Reddy, T., Lakshma Nayak, V., Prasad, B., Reddy, A.P., Ravikumar, A., Taj, S., Kamal, A. (2016). Design, synthesis and biological evaluation of N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1,3-diphenyl-1H-pyrazole-4-carboxamides as CDK1/Cdc2 inhibitors. European Journal of Medicinal Chemistry, 122, pp. 164-177.

  5. Gholap, H., Warule, S., Sangshetti, J., Kulkarni, G., Banpurkar, A., Satpute, S., Patil, R. (2016). Hierarchical nanostructures of Au@ZnO: antibacterial and antibiofilm agent. Applied Microbiology and Biotechnology, 100 (13), pp. 5849-5858.

  6. Jasti, V.P. Sharma, S. Althaus, I. Weinstein, A. Ramani, S. Canman, C. (2017). Repairing Interstrand DNA Crosslinks (ICL): Characterization of an ICL Incision/Lesion Bypass Polymerase Complex regulated by the Fanconi anemia pathway FASEB J. 31:996.3

  7. Kamble, R.D., Meshram, R.J., Hese, S.V., More, R.A., Kamble, S.S., Gacche, R.N., Dawane, B.S. (2016). Synthesis and in silico investigation of thiazoles bearing pyrazoles derivatives as anti-inflammatory agents Computational Biology and Chemistry, 61, pp. 86-96.

  8. Kamble, S., Utage, B., Mogle, P., Kamble, R., Hese, S., Dawane, B., Gacche, R. (2016). Evaluation of Curcumin Capped Copper Nanoparticles as Possible Inhibitors of Human Breast Cancer Cells and Angiogenesis: a Comparative Study with Native Curcumin AAPS PharmSciTech, 17 (5), pp. 1030-1041.

  9. Kathwate, G.H., Karuppayil, S.M. (2016).Tramadol, an Opioid Receptor Agonist: An Inhibitor of Growth, Morphogenesis, and Biofilm Formation in the Human Pathogen, Candida albicans. Assay and Drug Development Technologies, 14 (10), pp. 567-572.

  10. Khan, F.A.K., Jadhav, K.S., Patil, R.H., Shinde, D.B., Arote, R.B., Sangshetti, J.N. (2016). Biphenyl tetrazole-thiazolidinediones as novel bacterial peptide deformylase inhibitors: Synthesis, biological evaluations and molecular docking study. Biomedicine and Pharmacotherapy, 83, pp. 1146-1153.

  11. Khan, F.A.K., Patil, R.H., Patil, M., Arote, R., Shinde, D.B., Sangshetti, J.N. (2016). Bacterial Peptide Deformylase Inhibition of Tetrazole-Substituted Biaryl Acid Analogs: Synthesis, Biological Evaluations, and Molecular Docking Study. Archiv der Pharmazie, 349 (12), pp. 934-943.

  12. Khan, F.A.K., Patil, R.H., Shinde, D.B., Sangshetti, J.N. (2016). Design and synthesis of 4′-((5-benzylidene-2,4-dioxothiazolidin-3-yl)methyl)biphenyl-2-carbonitrile analogs as bacterial peptide deformylase inhibitors. Chemical Biology and Drug Design, 88 (6), pp. 938-944.

  13. Khan, F.A.K., Patil, R.H., Shinde, D.B., Sangshetti, J.N. (2016).Bacterial Peptide deformylase inhibition of cyano substituted biaryl analogs: Synthesis, in vitro biological evaluation, molecular docking study and in silico ADME prediction.Bioorganic and Medicinal Chemistry, 24 (16), pp. 3456-3463.

  14. Kim, J., Vaish, V., V., V., Feng, M., Field, K., Chatzistamou, I., Shim, M. (2016). Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice.Aging, 8 (10), pp. 2392-2406.

  15. Kulkarni, A.P., Mittal, S.P.K. (2016). Sequence data mining in search of hookworm (Necator americanus) microRNAs. Gene, 590 (2), pp. 317-323.

  16. Kumar, G.B., Nayak, V.L., Sayeed, I.B., Reddy, V.S., Shaik, A.B., Mahesh, R., Baig, M.F., Shareef, M.A., Ravikumar, A., Kamal, A. (2016). Design, synthesis of phenstatin/isocombretastatin-oxindole conjugates as antimitotic agents. Bioorganic and Medicinal Chemistry, 24 (8), pp. 1729-1740.

  17. Mathai, J., Mittal, S.P.K., Alam, A., Ranade, P., Mogare, D., Patel, S., Saxena, S., Ghorai, S., Kulkarni, A.P., Chattopadhyay, S. (2016). SMAR1 binds to T(C/G) repeat and inhibits tumor progression by regulating miR-371-373 cluster Scientific Reports, 6, art. no. 33779.

  18. Mittal, S.P.K., Khole, S., Jagadish, Ravikumar, A. N., Ghosh, D., Gadgil, V., Sinkar, V., Ghaskadbi, S.S. (2016). Andrographolide protects liver cells from H2O2 induced cell death by upregulation of Nrf-2/HO-1 mediated via adenosine A2a receptor signalling. Biochimica et Biophysica Acta - General Subjects, 1860 (11), pp. 2377-2390.

  19. Mogle, P.P., Meshram, R.J., Hese, S.V., Kamble, R.D., Kamble, S.S., Gacche, R.N., Dawane, B.S. (2016). Synthesis and molecular docking studies of a new series of bipyrazol-yl-thiazol-ylidene-hydrazinecarbothioamide derivatives as potential antitubercular agents MedChemComm, 7 (7), pp. 1405-1420.

  20. Niels Frank Jensen, N.F. Agama, K. Roy, A. Smith, D. H. Pfister, T. D. Unni Rømer, M. Zhang, H.L. Doroshow, J.H. Knudsen, B.R. Stenvang, J. Brünne N. Pommier Y. (2016). Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistanceassociated mutations. Journal of Experimental & Clinical Cancer Research, 35:56.

  21. Patil, K.K., Meshram, R.J., Dhole, N.A., Gacche, R.N. (2016). Role of dietary flavonoids in amelioration of sugar induced cataractogenesis Archives of Biochemistry and Biophysics, 593, pp. 1-11.

  22. Patil, K.K., Meshram, R.J., Gacche, R.N. (2016). Effect of monohydroxylated flavonoids on glycation-induced lens opacity and protein aggregation Journal of Enzyme Inhibition and Medicinal Chemistry, 31, pp. 148-156.

  23. Sagarkar, S., Gandhi, D., Devi, S.S., Sakharkar, A., Kapley, A. (2016). Atrazine exposure causes mitochondrial toxicity in liver and muscle cell lines. Indian Journal of Pharmacology, 48 (2), pp. 200-207.

  24. Sagarkar, S., Sakharkar, A. (2016). Epigenetics and alcohol use disorders. Neuropsychiatric Disorders and Epigenetics, pp. 361-397.

  25. Sakharkar, A.J., Vetreno, R.P., Zhang, H., Kokare, D.M., Crews, F.T., Pandey, S.C. (2016). A role for histone acetylation mechanisms in adolescent alcohol exposure-induced deficits in hippocampal brain-derived neurotrophic factor expression and neurogenesis markers in adulthood. Brain Structure and Function, 221 (9), pp. 4691-4703. Khan, F.A.K., Jadhav, K.S., Patil, R.H., Shinde, D.B., Arote, R.B., Sangshetti, J.N. (2016). Biphenyl tetrazole-thiazolidinediones as novel bacterial peptide deformylase inhibitors: Synthesis, biological evaluations and molecular docking study. Biomedicine and Pharmacotherapy, 83, pp. 1146-1153.

  26. Sangshetti, J.N., Kalam Khan, F.A., Kulkarni, A.A., Patil, R.H., Pachpinde, A.M., Lohar, K.S., Shinde, D.B. (2016). Antileishmanial activity of novel indolyl-coumarin hybrids: Design, synthesis, biological evaluation, molecular docking study and in silico ADME prediction. Bioorganic and Medicinal Chemistry Letters, 26 (3), pp. 829-835.

  27. Satpute, S.K., Banpurkar, A.G., Banat, I.M., Sangshetti, J.N., Patil, R.H., Gade, W.N. (2016). Multiple roles of biosurfactants in biofilms. Current Pharmaceutical Design, 22 (11), pp. 1429-1448.

  28. Satpute, S.K., Kulkarni, G.R., Banpurkar, A.G., Banat, I.M., Mone, N.S., Patil, R.H., Cameotra, S.S. (2016). Biosurfactant/s from Lactobacilli species: Properties, challenges and potential biomedical applications. Journal of Basic Microbiology, 56 (11), pp. 1140-1158.

  29. Shaikh, R.U., Dawane, A.A., Pawar, R.P., Gond, D.S., Meshram, R.J., Gacche, R.N. (2016). Inhibition of Helicobacter pylori and Its Associate Urease by Labdane Diterpenoids Isolated from Andrographis paniculata Phytotherapy Research, 30 (3), pp. 412-417.

  30. Shaikh, R.U., Pund, M.M., Gacche, R.N. (2016). Evaluation of anti-inflammatory activity of selected medicinal plants used in Indian traditional medication system in vitro as well as in vivo Journal of Traditional and Complementary Medicine, 6 (4), pp. 355-361.

  31. Sharma, S., Mathew, A.B., Chugh, J. (2017).miRNAs: Nanomachines That Micromanage the Pathophysiology of Diabetes Mellitus. Advances in Clinical Chemistry, 82, pp. 199-264.

  32. Srikanth, P.S., Nayak, V.L., Suresh Babu, K., Kumar, G.B., Ravikumar, A., Kamal, A. (2016). 2-Anilino-3-Aroylquinolines as Potent Tubulin Polymerization Inhibitors. ChemMedChem, pp. 2050-2062.

  33. Tembe S, Ghosh P, Sukhi S. (2017). Influence of methylation on the bacterial efflux pump-inducing property of triclosan. Journal of Hospital Infection , Volume 0 , Issue 0 ,

  34. Teppen, T.L., Krishnan, H.R., Zhang, H., Sakharkar, A.J., Pandey, S.C. (2016). The Potential Role of Amygdaloid MicroRNA-494 in Alcohol-Induced Anxiolysis. Biological Psychiatry, 80 (9), pp. 711-719.

  35. Tien, N.T., Karaca, I., Tamboli, I.Y., Walter, J. (2016). Trehalose alters subcellular trafficking and the metabolism of the Alzheimer-associated amyloid precursor protein. Journal of Biological Chemistry, 291 (20), pp. 10528-10540.

  36. Vaish, V., Kim, J., Shim, M. (2016). Lentivirus-mediated somatic recombination and development of a novel mouse model for sporadic colorectal cancer. Genes Chromosomes and Cancer, 55 (7), pp. 577-590.

  37. Zaheer, Z., Khan, F.A.K., Sangshetti, J.N., Patil, R.H., Lohar, K.S. (2016). Novel amalgamation of phthalazine–quinolines as biofilm inhibitors: One-pot synthesis, biological evaluation and in silico ADME prediction with favorable metabolic fate. Bioorganic and Medicinal Chemistry Letters, 26 (7), pp. 1696-1703.


  1. Pal, J.K., Rao, S.J. and Godbole, D.J. (2015). Detection of blotted proteins on nitrocellulose/PVDF membranes by Alta. Methods Mol Biol. 1314, 279-285. In Detection of Blotted Proteins: Methods and Protocols (eds. Kurien, B.T. and Scofield, R.H.), Humana Press, New York. doi: 10.1007/978-1-4939-2718-0_29.

  2. Ghosh S., Jagtap S., More P., Shete U.J., Maheshwari N.O., Rao S. J., Kitture R., Kale S., Bellare J.R., Patil S., Pal J.K. and Chopade B.A. (2015). Dioscorea bulbifera mediated synthesis of novel AucoreAgshell nanoparticles with potent antibiofilm and antileishmanial activity. J. Nanomaterials http://dx.doi.org/10.1155/2015/562938.

  3. Bhatia P, Raina S, Chugh J and Sharma S. miRNAs: Early prognostic biomarkers for Type 2 Diebetes Mellitus? Biomarkers in Medicine. 2015; In press.

  4. Rajendra R, Bhatia P, Justin A, Sharma S, Ballav N. Homogeneously-Alloyed Gold-Silver Nanoparticles as per Feeding Moles. J Phys Chem C. 2015; 119(10): 5604-13.

  5. Manisha Karani, Ravindranath Shashidhar, Aarti Kakatkar, Raj Kamal Gautam, Shibani Sukhi, Lipika Pansare-Godambe, Jayant Bandekar (2015). Radiation-resistant Macrococcus caseolyticus (A) isolated from radiation-processed semidried prawns. Canadian Journal of Microbiology, 61(1): 89-92, 10.1139/cjm-2014-0636

  6. Avneesh Kumar Gautam, Yogesh Panse, Payel Ghosh, Malik Johid Reza, Jayati Mullick, Arvind Sahu, Mutational analysis of Kaposica reveals that bridging of MG2 and CUB domains of target protein is crucial for the cofactor activity of RCA proteins, PNAS (2015) In Press.

  7. Patil R, Gholap H, Warule S, Banpurkar A, Kulkarni G, Gade G. (2015) Quantum dots conjugated zinc oxide nanosheets: Impeder of microbial growth and biofilm. Applied Surface Science 326: 73-81.

  8. Antileishmanial drug discovery: comprehensive review of the last 10 years JN Sangshetti, FAK Khan, AA Kulkarni, R Arote, RH Patil RSC Advances 5 (41), 32376-32415, 2015.

  9. Biofilm inhibition of linezolid-like Schiff bases: Synthesis, biological activity, molecular docking and in silico ADME prediction, JN Sangshetti, FAK Khan, RH Patil, SD Marathe, WN Gade, DB Shinde, Bioorganic & medicinal chemistry letters, 15; 25(4):874-80, 2015.

  10. Innovative biofilm inhibition and anti-microbial behavior of molybdenum sulfide nanostructures generated by microwave-assisted solvothermal route, N Qureshi, R Patil, M Shinde, G Umarji, V Causin, W Gade, U Mulik, A Bhalerao, DP Amalnerkar Applied Nanoscience, 5:331–341, 2015


  1. Sonali Rohamare, Sushama Gaikwad, Dafydd Jones, Varsha Bhavnani, Jayanta Pal, Ranu Sharma, Prathit Chatterjee (2014). Cloning, expression and in silico studies of a serine protease from a marine actinomycete (Nocardiopsis sp. NCIM 5124). Process Biochemistry 50, 378-387.

  2. Pal, Jayanta K. and Chatterjee, Sangeeta (2014). Translation regulation of gene expression and human diseases. In Gene and its Engineering (ed. Das, H.K.). Chapter 15, pp. 219-233. Wiley India, New Delhi.

  3. Pal, Jayanta K. and Chatterjee, Sangeeta (2014). Translation of mRNA into protein: Classic and recent experiments. In Gene and its Engineering (ed. Das, H.K.).Chapter 14, 194-218. Wiley India, New Delhi.

  4. Mittal, Smriti P.K., Kulkarni, Abhijeet P., Mathai, Jinumary, Chattopadhyay, Samit and Pal, J.K. (2014). Dose-dependent differential response of mammalian cells to cytoplasmic stress is mediated through the heme-regulated eIF-2a kinase.Int. J. Biochem. Cell Biol.54, 186-197.

  5. Godbole, D. Coux, O. and Pal, J.K. (2014). Tyrosinase Degradation in Amelanotic Melanoma Cells is mediated by cytoplasmic factors in addition to proteasome-mediated mechanism. Proc. Natl. Acad Sci. India Section B: Biol. Sci.10.1007_s40011-014-0358-z.

  6. Atoshi Banerjee, Ronald Benjamin, KannanBalakrishnan, PayelGhosh, Sharmistha Banerjee, Human protein Staufen-2 promotes HIV-1 proliferation by positively regulating RNA export activity of viral protein Rev, Retrovirology (2014), 11:18.

  7. Ghosh A, Banerjee T, Bhandary S and Surolia A. Formulation of nanotized curcumin and demonstration of its anti-malarial efficacy. (2014) International Journal of Nanomedicine, 9, 5373-5387

  8. Watanabe S, Pinto JM, Bashir ME, De Tineo M, Suzaki H, Baroody FM, Naclerio RM, Sharma S$. Effect of Prednisone on Nasal Symptoms and Peripheral Blood T-cell Function in Chronic Rhinosinusitis. Int Forum Allergy Rhinol. 2014; 4(8):609-16.

  9. Nanostructured microspheres of silver@ zinc oxide: an excellent impeder of bacterial growth and biofilm, SS Patil, RH Patil, SB Kale, MS Tamboli, JD Ambekar, WN Gade, SS Kolekar, BB Kale. Journal of Nanoparticle Research 16:2717, 2014.

  10. Proteomics of arsenic stress in the gram-positive organism Exiguobacterium sp. PS NCIM 5463, P Sacheti, R Patil, A Dube, H Bhonsle, D Thombre, S Marathe, R Vidhate, P Wagh, M Kulkarni, S Rapole, W Gade., Applied microbiology and biotechnology 98 (15), 6761-6773, 2014.

  11. Biomineralized Anisotropic Gold Microplate–Macrophage Interactions Reveal Frustrated Phagocytosis-like Phenomenon: A Novel Paclitaxel Drug Delivery Vehicle, AV Singh, M Batuwangala, R Mundra, K Mehta, S Patke, E Falletta, R Patil, WN Gade., ACS applied materials & interfaces 6 (16), 14679-14689

  12. Synthesis, Antileishmanial Activity and Docking Study of N′-Substitutedbenzylidene-2-(6, 7-dihydrothieno [3, 2-C] pyridin-5 (4H)-yl) acetohydrazides, JN Sangshetti, RI Shaikh, FAK Khan, RH Patil, SD Marathe, WN Gade, DB Shinde, Bioorganic & medicinal chemistry letters 24 (6), 1605-1610, 2014.

  13. Cost effective technologies and renewable substrates for biosurfactants’ production IM Banat, SK Satpute, SS Cameotra, R Patil, NV Nyayanit, Frontiers in microbiology 5, 2014.

  14. Self assembly of nanostructured hexagonal cobalt dendrites: an efficient anti-coliform agent, RP Panmand, RH Patil, BB Kale, LK Nikam, MV Kulkarni, DK Thombre, WN Gade, SW Gosavi, RSC Advances 4 (9), 4586-4595, 2014.


  1. Joshi, Manali, Kulkarni, Abhijeet and Pal, Jayanta K. (2013). Small molecule modulators of eukaryotic initiation factor 2a kinases, the key regulators of protein synthesis. Biochimie95, 1980-1990.

  2. Mittal, Smriti P.K., Mathai, Jinumary, Kulkarni, Abhijeet P., Pal, J.K. and Chattopadhyay, Samit. (2013). Mir-320a regulates erythroid differentiation through MAR binding protein SMAR1. Int. J. Biochem. Cell Biol.45, 2519-2529.

  3. Chatterjee, S., Panda, A.C., Berwal, S., Sreejith, R.K., Ritvika, C., Seshadri,V. and Pal, J.K. (2013). Vimentin is a component of a complex that binds to the 5'UTR of human heme-regulated eIF2a kinase mRNA and regulates its translation. FEBS Lett.587, 474-480.

  4. Tank, C., Raman, S., Karan, S., Gosavi, S., Lalla, N.P., Sathe, V., Berndt, R., Gade, W.N., Bhoraskar, S.V., Mathe, V.L. (2013). Antimicrobial activity of silica coated silicon nano-tubes (SCSNT) and silica coated silicon nano-particles (SCSNP) synthesized by gas phase condensation. J Mater Sci Mater Med 14, 14.

  5. PoonamSacheti, HemangiBhonsle, RajendraPatil, Mahesh J. Kulkarni, RapoleSrikanth, WasudevGade (2013). Arsenomics of Exiguobacterium sp. PS (NCIM 5463). RSC Advances 10.1039/c0xx00000x

  6. HaribhauGholap ,RajendraPatil , Prasad Yadav , ArunBanpurkar , SatishchandraOgale, WasudeoGade (2013). CdTe-TiO2Nanocomposite: An Impeder of Bacterial Growth and Biofilm. IOP Nanotechnology 24,195109


  1. Pal, J.K., Berwal, S.K. and Soni, R.N. (2012). A single-step simultaneous protein staining procedure for polyacrylamide gels and nitrocellulose membranes by alta during Western blot analysis. Methods Mol Biol. 869, 551-559. In Protein Electrophoresis: Methods and Protocols (eds. Kurien, B.T. and Scofield, R.H.), Humana Press, New York.

  2. Sinha, Surajit, Malonia, Sunil Kumar, Mittal, Smriti P.K., Mathai, Jinumary, Pal, Jayanta K. and Chattopadhyay, Samit (2012). Chromatin remodelling protein SMAR1 inhibits p53 dependent transactivation by regulating acetyl transferase p300. Int. J. Biochem. Cell Biol.44, 46-52.

  3. Sreejith, R.K., C. G. Suresh, Siddharth H. Bhosale, VarshaBhavnani, Avinash Kumar, Sushama M. Gaikwad and Jayanta K. Pal (2012). Conformational transitions of the catalytic domain of heme-regulated eukaryotic initiation factor 2α kinase, a key translational regulatory molecule. J. Fluorescence22, 431-441.

  4. Shinde, M., Patil, R., Karmakar, S., Bhoraskar, S., Rane, S., Gade W.N., Amalnerkar, D.(2012). Antimicrobial properties of uncapped silver nanoparticles synthesized by DC arc thermal plasma technique.J Nanosci Nanotechnol. 12, 887-893

  5. Tamboli, M.S., Kulkarni, M.V., Patil, R.H., Gade, W.N., Navale, S.C., Kale, B.B. (2012). Nanowires of silver-polyanilinenanocompositesynthesized via in situ polymerization and its novel functionality as an antibacterial agent.Colloids Surf B Biointerfaces 92, 35-41.

  6. Daware, V., Kesavan, S., Patil, R., Natu, A., Kumar, A., Kulkarni, M., Gade, W. (2012). Effects of arsenite stress on growth and proteome of Klebsiellapneumoniae. J Biotechnol. 158, 8-16.

  7. Wagh Nee Jagtap, M.S., Patil, R.H., Thombre, D.K., Kulkarni, M.V., Gade, W.N., Kale, B.B. (2012). Evaluation of anti-quorum sensing activity of silver nanowires.ApplMicrobiolBiotechnol 8, 8.

  8. Kamat, S., Khot, M., Zinjarde, S., Ravikumar, A., Gade, W.N. (2012). Coupled production of single cell oil as biodiesel feedstock, xylitol and xylanase from sugarcane bagasse in a biorefinery concept using fungi from the tropical mangrove wetlands.BioresourTechnol 23, 01742-01747.

  9. Singh, A.V., Vyas, V., Salve, T.S., Cortelli, D., Dellasega, D., Podesta, A., Milani, P., Gade, W.N. (2012). Biofilm formation on nanostructured titanium oxide surfaces and a micro/nanofabrication-based preventive strategy using colloidal lithography.Biofabrication.4, 025001.doi: 025010.021088/021758-025082/025004/025002/025001. Epub 022012 Mar 025012.

  10. Singh, A.V., Khare, M., Gade, W.N., Zamboni, P. (2012). Theranostic implications of nanotechnology in multiple sclerosis: a future perspective. Autoimmune Dis 160830, 30.



  1. Molybdenum sulfide nanoparticles containing formulation. Qureshi Nilam, Shinde Manish, Umarji Govind, Patil Rajendra, Gade Wasudev, Mulik Uttamrao, and Amalnerkar Dinesh.2583/MuM/2011/dt 13 september 2011

  2. Ajay Vikram Singh, VarunVyas, RajendraPatil, Vimal Sharma, Pasquale EmanueleScopelliti, GeroBongiorno, Alessandro Podesta, Cristina Lenardi, WasudevNamdevGade, Paolo Milani (2011). Quantitative Characterization of the Influence of the Nanoscale Morphology of Nanostructured Surfaces on Bacterial Adhesion and Biofilm Formation, PLoS One, 6, 25029.

  3. Sushma Mane, WasudeoGade, SahayogJamdar (2011). Purification and characterization of prolineaminopeptidase from chicken Intestine Process Biochemistry46, 1384-1389.

  4. Poonam Gautam, Santosh Kumar Upadhyay, Wazid Hassan, Taruna Madan, Ravi Sirdeshmukh, Curam Sreenivasacharlu Sundaram, Wasudev Namdeo Gade, Seemi Farhat Basir, Yogendra Singh, Puranam Usha Sarma (2011). Transcriptomic and Proteomic Profile of Aspergillusfumigatus on Exposure to Artemisinin, Mycopathologia, 172, 331-346.


Patents: Pal, J. K., Godbole, D. and Sharma, K. (2010). “Method of staining proteins using Alta”. An United States Patent 7833797 (16th November, 2010)

  1. Chatterjee, S., Berwal, S.K. and Pal, J.K. (2010). Pathological variations in 5’-untranslated regions of human genes. Encyclopedia Life Sci. (Sept., 2010) [DOI:10.1002/9780470015902. a0022408]

  2. Berwal, S.K., Sreejith, R.K. and Pal, J.K. (2010). Distance between RBS and AUG plays an important role in overexpression of recombinant proteins. Anal. Biochem.405, 275-277.

  3. Pal, J.K., Chatterjee, S. and Berwal, S. K. (2010). Pathological variations in 3’-untranslated regions of human genes. Encyclopedia Life Sci. (March, 2010) [DOI:10.1002/9780470015902.a0022450].

  4. Kulkarni, Abhijeet P., Mittal, Smriti P.K., Devasagayam, T.P.A. and Pal, Jayanta K. (2010). Activation of the Heme Regulated eIF-2α Kinase is mediated by Hsp90 and Hsp70 during oxidative stress. Ind. J. Biochem. Biophys.47, 67-74.

  5. Sinha, S., Malonia, S.K., Mittal, S.P.K., Singh, K., Kadreppa, S. Kamat, R., Mukhopadhyay, R., Pal, J.K. and Chattopadhyay, S. (2010). Coordinated regulation of p53 apoptotic targets BAX and PUMA by SMAR1 through an identical MAR element. EMBO J. 29, 830-42.

  6. Sushma Mane, MadhujitDamle, PadmanabhakurupHarikumar, SahayogJamdar, SahayogJamdar, WasudeoGade (2010).Purification and characterization of aminopeptidase N from chicken intestine with potential application in debittering. Process Biochemistry45, 1011-1016.

  7. Ajay V Singh,RajendraPatil, Cristina Lenardi, Paolo Milani and W.N.Gade (2010). Biocompatible Nanomaterials: Synthesis, Characterization and Applications.Nanobiomaterial Applications in Tissue Repair and Ulcer Management: A New Role for Nanomedicine , Chapter 4.

  8. Ajay V Singh RajendraPatil, Atul, Paolo Milani, W.N.Gade (2010). Biological synthesis of copper oxide nanoparticles using E.coli.Current nanoscience, vol 6,345-365.


  1. Sreejith, R.K., Yadav, V.N., Varshney, N.K., Berwal, S.K., Suresh, C.G., Gaikwad, S.M. and Pal, J.K. (2009). Conformational characterization of human eukaryotic initiation factor 2a: A single tryptophan protein. Biochem. Biophys. Res. Commun. 390, 273-279.

  2. Kulkarni, Abhijeet P., Mittal, Smriti P.K., Devasagayam, T.P.A. and Pal, Jayanta K. (2009). Oxidative Stress perturbs cell proliferation in human K562 cells by modulating protein synthesis and cell cycle. Free Radical Research43, 1090-110.

  3. Chatterjee, S. and Pal, J.K. (2009). The role of 5’- and 3’-UTR of mRNAs in human diseases. Biol. Cell101, 251-262.

  4. Singh, Vir B., Pavitra, L., Chattopadhyay, Samit and Pal, Jayanta K. (2009). Stress-induced overexpression of the heme-regulated human eIF-2a kinase is regulated by Elk-1, activated through ERK pathway. Biochem. Biophys. Res. Commun. 379, 710-715.

  5. Singh AV, Patil R, Kasture MB, Gade W.N, Prasad BL. (2009). Synthesis of Ag-Pt alloy nanoparticles in aqueous bovine serum albumin foam and their cytocompatibility against human gingival fibroblasts.Colloids Surf B Biointerfaces 69(2), 239-45.

Book : Pal, Jayanta K. and Ghaskadbi, Saroj S. (2009). Fundamentals of Molecular Biology. pp. 1- 408. Oxford University Press (New Delhi).

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